Bhanji S, Roy G A, Baulieu C
Acta Psychiatr Scand. 1978 Nov;58(5):379-83. doi: 10.1111/j.1600-0447.1978.tb03569.x.
Recent work suggests that depriving endogenous depressives of sleep for 1 night may be followed by an alleviation of their illness. In order to facilitate further study of the mechanisms underlying this effect, hourly self-rated measurements of mood were obtained throughout the sleepless night and the time of onset of any response noted. Of the patients who improved, some did so during the day following sleep deprivation; in others the response did not occur until after the next night's sleep. The two groups of responders differed in terms of self-reported emotional arousal during the course of the sleepless night. The implications of these findings are discussed in relation to further studies of sleep deprivation therapy.
近期研究表明，让内源性抑郁症患者连续一晚不睡觉，其病情可能会有所缓解。为了便于进一步研究这种效应背后的机制，在整个无眠之夜每小时对患者的情绪进行自我评估，并记录任何反应出现的时间。在病情有所改善的患者中，一些人是在睡眠剥夺后的白天病情好转；而另一些人的反应直到第二天晚上睡眠之后才出现。这两组病情好转的患者在无眠之夜的自我报告情绪唤醒方面存在差异。结合睡眠剥夺疗法的进一步研究对这些发现的意义进行了讨论。
