英国印支难民中的乙型肝炎
Hepatitis B among Indochinese refugees in Great Britain.
作者信息
Chadwick R G, Hall A J, Davidson I, Bull F G, Wright R
出版信息
Postgrad Med J. 1982 Nov;58(685):676-9. doi: 10.1136/pgmj.58.685.676.
Six hundred and thirty-two blood samples from 879 consecutive admissions to one resettlement camp for Indochinese refugees in Great Britain were screened for markers of hepatitis B (HB) virus infection. The overall prevalence of HB surface antigen (HBsAg) was 15%, being 16% in those aged 40 years or less, and falling to 8% in those older than 40 (P less than 0.05). No significant difference in prevalence was found between males and females. HBe antigen was detected in 56% of those with HBsAg and was demonstrable in 55-76% of those under 30 years of age. HBe antibody was found in 21% of HBsAg-positive refugees. In those under 40 years old, HB core (HBc) antibody was commoner in males (P less than 0.01). HBc antibody prevalence increased significantly with age in females (P less than 0.01) but not in males. There was no definite evidence that vertical transmission of hepatitis B was present in the group studied.
对英国一个印度支那难民安置营连续收治的879名患者的632份血样进行了乙肝（HB）病毒感染标志物筛查。HB表面抗原（HBsAg）的总体流行率为15%，40岁及以下人群中为16%，40岁以上人群中降至8%（P<0.05）。男女之间的流行率无显著差异。在56%的HBsAg阳性者中检测到HBe抗原，在30岁以下人群中，55%-76%的人可检测到该抗原。在HBsAg阳性难民中，21%的人发现有HBe抗体。在40岁以下人群中，男性的HB核心（HBc）抗体更为常见（P<0.01）。女性中HBc抗体流行率随年龄显著增加（P<0.01），而男性中则不然。在所研究的人群中，没有确凿证据表明存在乙肝垂直传播。
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