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血管加压素和催产素在大脑中的释放——一种突触事件。

Vasopressin and oxytocin release in the brain--a synaptic event.

作者信息

Buijs R M, Van Heerikhuize J J

出版信息

Brain Res. 1982 Dec 2;252(1):71-6. doi: 10.1016/0006-8993(82)90979-9.

DOI:10.1016/0006-8993(82)90979-9
PMID:7172022
Abstract

In order to obtain evidence for a central release of vasopressin and oxytocin, the release of these peptides was demonstrated in various extrahypothalamic areas of the rat brain. It proved that in those areas where these peptidergic fibers terminate synaptically a vasopressin and/or oxytocin calcium-dependent release, similar to that in the neurohypophysis, could be evoked by potassium or veratridine. Such release was not found in areas in which these fibers do not exhibit synaptic specialization.

摘要

为了获得血管加压素和催产素中枢释放的证据,在大鼠脑的各个下丘脑外区域证实了这些肽的释放。结果证明,在这些肽能纤维发生突触终末的区域,钾离子或藜芦碱能够诱发血管加压素和/或催产素的钙依赖性释放,这与神经垂体中的释放情况相似。而在这些纤维未表现出突触特化的区域则未发现这种释放现象。

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