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Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets.黑色素细胞和黑色素瘤的表面抗原。黑色素细胞分化标志物和黑色素瘤亚群。
J Exp Med. 1982 Dec 1;156(6):1755-66. doi: 10.1084/jem.156.6.1755.
2
Surface antigens of melanomas and melanocytes defined by mouse monoclonal antibodies: specificity analysis and comparison of antigen expression in cultured cells and tissues.由小鼠单克隆抗体定义的黑色素瘤和黑色素细胞的表面抗原：培养细胞和组织中抗原表达的特异性分析与比较
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Cell surface antigens of human melanocytes and melanoma. Expression of adenosine deaminase binding protein is extinguished with melanocyte transformation.人类黑素细胞和黑色素瘤的细胞表面抗原。随着黑素细胞转化，腺苷脱氨酶结合蛋白的表达消失。
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In vitro differentiation of human melanoma cells analyzed with monoclonal antibodies.用人黑色素瘤细胞的体外分化，采用单克隆抗体进行分析。
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Cell surface antigens of melanocytes and melanoma.黑色素细胞和黑色素瘤的细胞表面抗原。
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Metastatic Melanoma of Uncertain Primary with 5-Year Durable Response after Conventional Therapy: A Case Report with Literature Review.常规治疗后出现5年持久缓解的原发灶不明转移性黑色素瘤：一例报告并文献复习
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本文引用的文献

1
THE AKR THYMIC ANTIGEN AND ITS DISTRIBUTION IN LEUKEMIAS AND NERVOUS TISSUES.AKR胸腺抗原及其在白血病和神经组织中的分布。
J Exp Med. 1964 Sep 1;120(3):413-33. doi: 10.1084/jem.120.3.413.
2
ANTIGENIC PROPERTIES OF EXPERIMENTAL LEUKEMIAS. I. SEROLOGICAL STUDIES IN VITRO WITH SPONTANEOUS AND RADIATION-INDUCED LEUKEMIAS.实验性白血病的抗原特性。I. 对自发性和辐射诱发白血病的体外血清学研究。
J Natl Cancer Inst. 1963 Oct;31:977-95.
3
Immunoelectron microscopic identification of Langerhans cells using a new antigenic marker.使用一种新的抗原标志物对朗格汉斯细胞进行免疫电子显微镜鉴定。
J Invest Dermatol. 1982 Feb;78(2):177-80. doi: 10.1111/1523-1747.ep12506352.
4
Heterogeneity in surface antigen and glycoprotein expression of cell lines derived from different melanoma metastases of the same patient. Implications for the study of tumor antigens.源自同一患者不同黑色素瘤转移灶的细胞系表面抗原和糖蛋白表达的异质性。对肿瘤抗原研究的启示。
J Exp Med. 1981 Dec 1;154(6):1764-78. doi: 10.1084/jem.154.6.1764.
5
Selective proliferation of normal human melanocytes in vitro in the presence of phorbol ester and cholera toxin.在佛波酯和霍乱毒素存在的情况下，正常人黑素细胞在体外的选择性增殖。
Proc Natl Acad Sci U S A. 1982 Mar;79(6):2018-22. doi: 10.1073/pnas.79.6.2018.
6
Cell surface antigens of human renal cancer defined by mouse monoclonal antibodies: identification of tissue-specific kidney glycoproteins.用小鼠单克隆抗体鉴定的人肾癌细胞表面抗原：组织特异性肾糖蛋白的鉴定
Proc Natl Acad Sci U S A. 1981 Aug;78(8):5122-6. doi: 10.1073/pnas.78.8.5122.
7
Cell surface antigens of human malignant melanoma: definition of six antigenic systems with mouse monoclonal antibodies.人类恶性黑色素瘤的细胞表面抗原：用小鼠单克隆抗体对六种抗原系统的定义
Proc Natl Acad Sci U S A. 1980 Oct;77(10):6114-8. doi: 10.1073/pnas.77.10.6114.
8
Serological survey of normal humans for natural antibody to cell surface antigens of melanoma.对正常人进行黑色素瘤细胞表面抗原天然抗体的血清学调查。
Proc Natl Acad Sci U S A. 1980 Jul;77(7):4260-4. doi: 10.1073/pnas.77.7.4260.
9
Analysis of the biosynthesis of HLA-DR glycoproteins in human malignant melanoma cell lines.人恶性黑色素瘤细胞系中HLA - DR糖蛋白生物合成的分析
J Immunol. 1981 Jun;126(6):2408-13.
10
Cell surface antigens of human astrocytoma defined by mouse monoclonal antibodies: identification of astrocytoma subsets.用小鼠单克隆抗体鉴定的人星形细胞瘤细胞表面抗原：星形细胞瘤亚群的鉴定
Proc Natl Acad Sci U S A. 1982 Sep;79(18):5641-5. doi: 10.1073/pnas.79.18.5641.

黑色素细胞和黑色素瘤的表面抗原。黑色素细胞分化标志物和黑色素瘤亚群。

Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets.

作者信息

Houghton A N, Eisinger M, Albino A P, Cairncross J G, Old L J

出版信息

J Exp Med. 1982 Dec 1;156(6):1755-66. doi: 10.1084/jem.156.6.1755.

DOI:10.1084/jem.156.6.1755
PMID:7175440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2186870/
Abstract

The surface antigens of melanocytes from newborn and adult skin have been analyzed with monoclonal antibodies detecting cell surface antigens of malignant melanoma. Antigenic markers that distinguish early, intermediate, and mature stages in melanocyte differentiation have been defined. The characteristics of the normal melanocyte precursor have been inferred from the features of melanomas that express early markers of melanocyte differentiation. A rudimentary surface antigen map of cells undergoing melanocyte differentiation and a new classification of melanomas based on the expression of melanocyte differentiation antigens are proposed.

摘要

利用检测恶性黑色素瘤细胞表面抗原的单克隆抗体，对新生儿和成人皮肤黑素细胞的表面抗原进行了分析。已确定了区分黑素细胞分化早期、中期和成熟阶段的抗原标志物。从表达黑素细胞分化早期标志物的黑色素瘤特征中推断出正常黑素细胞前体的特征。提出了黑素细胞分化细胞的初步表面抗原图谱以及基于黑素细胞分化抗原表达的黑色素瘤新分类。