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Comparison of three different assays for the assessment of ciguatoxin in fish tissues: radioimmunoassay, mouse bioassay and in vitro guinea pig atrium assay.

作者信息

Kimura L H, Hokama Y, Abad M A, Oyama M, Miyahara J T

出版信息

Toxicon. 1982;20(5):907-12. doi: 10.1016/0041-0101(82)90078-2.

DOI:10.1016/0041-0101(82)90078-2
PMID:7179296
Abstract

Moderate correlation was shown between the following tests: RIA: mouse bioassay (r = 0.58); RIA: guinea pig atrium assay (r = 0.62); guinea pig atrium assay: mouse bioassay (r = 0.62). All three assay procedures showed good correlation when ciguatoxin was present in tissues in high concentrations. The results also suggest that more than one structurally related toxin may be present in the fish tissues.

摘要

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