横纹肌溶解症和急性肾衰竭中肌肉钙化的消退

Resolution of muscle calcification in rhabdomyolysis and acute renal failure.

作者信息

Akmal M, Goldstein D A, Telfer N, Wilkinson E, Massry S G

出版信息

Ann Intern Med. 1978 Dec;89(6):928-30. doi: 10.7326/0003-4819-89-6-928.

Abstract

We studied four patients with acute renal failure associated with nontraumatic rhabdomyolysis to evaluate the presence and progression of calcium deposits in damaged muscle tissue. Conventional and electron radiography and technetium-99m diphosphonate (TcDP) scans were done during the oliguric phase of acute renal failure and repeated after renal function returned to normal. Three patients showed deposits of calcium by conventional radiography and all by electron radiography and TcDP during the oliguric period. When the patients recovered renal function and muscle injuries healed, calcium deposits disappeared. The results show that calcium deposits in damaged muscle occur during the oliguric phase of acute renal failure due to rhabdomyolysis and the calcification disappears with recovery of renal failure; and TcDP scans are the most sensitive method of detecting calcium deposits in these patients.

摘要

我们研究了4例与非创伤性横纹肌溶解症相关的急性肾衰竭患者，以评估受损肌肉组织中钙沉积的存在情况及进展。在急性肾衰竭的少尿期进行了传统X线摄影、电子放射摄影及锝-99m二膦酸盐（TcDP）扫描，并在肾功能恢复正常后重复进行。3例患者在少尿期通过传统X线摄影显示有钙沉积，通过电子放射摄影和TcDP扫描均显示有钙沉积。当患者肾功能恢复且肌肉损伤愈合时，钙沉积消失。结果表明，横纹肌溶解症所致急性肾衰竭少尿期，受损肌肉中会出现钙沉积，肾衰竭恢复后钙化消失；TcDP扫描是检测这些患者钙沉积最敏感的方法。