Dahlbäck M, Pauwels R, Bazin H, Bergstrand H
Allergy. 1982 Nov;37(8):569-80. doi: 10.1111/j.1398-9995.1982.tb02342.x.
Sprague Dawley rats were immunized with graded doses of ovalbumin (OA) together with alum. The capacity of the animals to produce a bronchial anaphylactic response to intravenous antigen challenge was related to serum OA-IgE and OA-IgG2a antibody levels estimated by radioimmunoassay. A significant correlation between bronchial anaphylactic response capacity and OA-IgE antibody levels was found under a few, but not all, of several carefully chosen experimental conditions. No correlation was demonstrable between the in vivo reactivity of the animals and their serum levels of OA-specific IgG2a antibodies.
将不同剂量的卵清蛋白（OA）与明矾一起用于免疫斯普拉格-道利大鼠。通过放射免疫测定法估算，动物对静脉注射抗原激发产生支气管过敏反应的能力与血清中OA-IgE和OA-IgG2a抗体水平相关。在几种精心挑选的实验条件下，发现支气管过敏反应能力与OA-IgE抗体水平之间在部分而非全部条件下存在显著相关性。动物的体内反应性与其血清中OA特异性IgG2a抗体水平之间未显示出相关性。
