Hammar H
Acta Derm Venereol. 1977;57(2):159-63.
Oral provocation test with cow's milk and cereals were performed in 81 children with atopic dermatitis, all below 5 years of age. In 15 of the children exacerbation of the dermatitis occurred on the second or third day after initiation of the tests. These patients, whose mean age was 13 months, underwent repeated provocation during the ensuring 18 months. Eleven children lost their sensitivity to the offending foods and 2 children became more tolerant during this period. Initial levels of serum IgE and specific reagins against the foods tested did not distinguish those patients who were positive to the provocation tests. In this group, however, reagins against egg white were significantly increased. The specific serum reagins were unaltered or increased in the majority of cases during the period of study. The radioallergosorbent test (RAST) was found of limited value as a screening tool in patients with atopic dermatitis in whom exacerbation of the condition appears to be caused by food sensitivity.
对81名年龄均在5岁以下的特应性皮炎患儿进行了牛奶和谷物的口服激发试验。在15名儿童中，试验开始后的第二天或第三天出现了皮炎加重的情况。这些平均年龄为13个月的患者在接下来的18个月内接受了反复激发试验。在此期间，11名儿童对引起过敏的食物失去了敏感性，2名儿童的耐受性增强。血清IgE的初始水平以及针对所测试食物的特异性反应素无法区分激发试验呈阳性的患者。然而，在这组患者中，针对蛋清的反应素显著增加。在研究期间，大多数病例的特异性血清反应素未发生变化或有所增加。对于病情加重似乎由食物敏感性引起的特应性皮炎患者，发现放射变应原吸附试验（RAST）作为一种筛查工具价值有限。
