Binder P S
Curr Eye Res. 1982;2(7):435-41. doi: 10.3109/02713688208996346.
We attempted to induce corneal flattening in a baboon model by implanting donut-shaped hydrogel lenses in an intralamellar pocket created by a microkeratome. 7mm diameter hydrogels in five eyes produced corneal steepening from 3.4 to 22.5 diopters. Three to five months postoperatively the study was terminated and the corneas studied with correlative microscopy. There was an absence of inflammation, but the intralamellar pocket was lined with keratocytes, focal areas of epithelial implantation were found and the overlying corneal cap was normal.
我们试图通过在微型角膜刀制作的板层内口袋中植入甜甜圈形状的水凝胶镜片，在狒狒模型中诱导角膜变平。五只眼睛植入直径7毫米的水凝胶后，角膜曲率从3.4屈光度增加到22.5屈光度。术后三到五个月，研究终止，对角膜进行相关显微镜检查。未发现炎症，但板层内口袋内衬有角膜细胞，发现了局灶性上皮植入区域，上方的角膜帽正常。
