Chow C W, Landau L I, Taussig L M
Eur J Pediatr. 1982 Dec;139(4):240-3. doi: 10.1007/BF00442171.
The size of bronchial mucous glands in 21 patients who presented with meconium ileus and died at less than three weeks of age were compared quantitatively with that of 28 control patients. There were no significant differences by most methods of comparison. However, pulmonary infection was seen in a higher percentage of cystic fibrosis patients. The absence of mucous gland hyperplasia at birth suggests that mucous obstruction of airways may not be primarily responsible for the increased susceptibility to respiratory tract infection in cystic fibrosis, but when present later in life may aggravate the infection.
对21例胎粪性肠梗阻且在3周龄内死亡的患儿与28例对照患儿的支气管黏液腺大小进行了定量比较。多数比较方法显示无显著差异。然而，囊性纤维化患者肺部感染的发生率更高。出生时无黏液腺增生表明，气道黏液阻塞可能不是囊性纤维化患者呼吸道感染易感性增加的主要原因，但在生命后期出现时可能会加重感染。
