Hodgkinson D J, ReMine W H, Weiland L H
Ann Surg. 1978 Nov;188(5):679-84. doi: 10.1097/00000658-197811000-00017.
Cystadenocarcinomas are rare tumors of the pancreas. They are half as common as their benign counterpart--the cystadenoma. A review of 21 cases, including eight reported since 1963, revealed that most patients presented with upper abdominal pain and a large palpable upper abdominal mass. All patients had evidence of malignant degeneration occurring in a mucous cystadenoma. None had evidence of a serious cystadenoma. Grading revealed a predominance of low-grade tumors: 20 of the 21 lesions were grade 1 or 2. Cystadenocarcinomas were slightly more frequent in the head of the pancreas. Four patients had metastasis. Complete excision by distal or total pancreatectomy or Whipple pancreaticoduodenectomy is recommended. The five year survival after complete excision is 68%, and for patients with grade 1 lesions, and five year survival is 64%.
囊腺癌是胰腺的罕见肿瘤。其发病率仅为良性对应物——囊腺瘤的一半。对21例病例的回顾，包括自1963年以来报告的8例，显示大多数患者表现为上腹部疼痛和可触及的上腹部肿块。所有患者均有黏液性囊腺瘤发生恶性变的证据。无一例有严重囊腺瘤的证据。分级显示低级别肿瘤占优势：21个病变中有20个为1级或2级。囊腺癌在胰头部位略为常见。4例患者发生转移。建议通过远端或全胰切除术或惠普尔胰十二指肠切除术进行完整切除。完整切除后的5年生存率为68%，1级病变患者的5年生存率为64%。
