Yanagisawa A, Ohashi K, Hori M, Takagi K, Kitagawa T, Sugano H, Kato Y
Department of Pathology, Cancer Institute, Tokyo.
Jpn J Cancer Res. 1993 Apr;84(4):474-9. doi: 10.1111/j.1349-7006.1993.tb00161.x.
A new type of mucinous cystic pancreatic neoplasm is described. The lesions, which have been recognized only recently with the progress of diagnostic techniques and have not previously been described in the literature, are characterized by multilocular cysts with papillary proliferation of the lining epithelium. They occur exclusively in the head and body, predominantly in males, and coexistence of well-differentiated adenocarcinoma as well as adenoma components is frequently encountered. These lesions are quite different from hitherto described mucinous cystic neoplasms of pancreas, not only in terms of gross features but also with regard to intrapancreatic location, and sex and age distributions. We propose to classify these lesions as a new pancreatic tumor entity: the ductectatic-type mucinous cystadenoma/cystadenocarcinoma.
本文描述了一种新型的胰腺黏液性囊性肿瘤。这些病变是随着诊断技术的进步最近才被认识到的,此前文献中未曾描述过,其特征为多房性囊肿,内衬上皮呈乳头状增生。它们仅发生于胰头和胰体,以男性为主,且常伴有高分化腺癌及腺瘤成分。这些病变不仅在大体特征方面,而且在胰腺内位置、性别和年龄分布方面,均与迄今所描述的胰腺黏液性囊性肿瘤有很大不同。我们建议将这些病变归类为一种新的胰腺肿瘤实体:导管扩张型黏液性囊腺瘤/囊腺癌。