Narita M, Loganathan P, Hussein A, Jamaluddin A, Joseph P G
Natl Inst Anim Health Q (Tokyo). 1982 Winter;22(4):170-9.
Sixteen goats were inoculated subcutaneously or intraperitoneally with cultured Pseudomonas pseudomallei isolated from a goat. They showed either acute or chronic phase of disease. When inoculated intraperitoneally, animals suffered from a septicemic illness of short duration accompanied with micro-abscesses scattered widely throughout the body. In animals subcutaneously inoculated no clinical signs were exhibited, but the disease was of rather long duration, and lesions were large and localized in the spleen and lungs. Coincident with lesions, a large number of Pseudomonas pseudomallei organisms were isolated from abscesses in the spleen and lungs. Ultrastructurally, numerous bacilli could be detected in the cytoplasm of macrophages in the abscesses. They had an electron-dense cell wall. Most of them were surrounded by electron-dense substance.
16只山羊通过皮下或腹腔注射接种了从一只山羊身上分离培养出的类鼻疽假单胞菌。它们呈现出疾病的急性期或慢性期。腹腔注射时，动物会患上病程短暂的败血病，伴有全身广泛散布的微脓肿。皮下接种的动物未表现出临床症状，但疾病持续时间较长，病变较大且局限于脾脏和肺部。与病变同时出现的是，从脾脏和肺部的脓肿中分离出大量类鼻疽假单胞菌。在超微结构上，脓肿中巨噬细胞的细胞质内可检测到大量杆菌。它们有一个电子致密的细胞壁。大多数杆菌被电子致密物质包围。
