Dolan L A
Vet Rec. 1980 Mar 15;106(11):241-3. doi: 10.1136/vr.106.11.241.
Of 272 heifers subjected to a brucellosis anamnestic test following one injection of K45/20A vaccine, 53 (19%) gave a positive result to the anti-bovine globulin test and 21 (8%) gave a complement fixation test titre at 1/16 or more. Three heifers (1%) gave a positive serum agglutination test (SAT) titre (60 iu or more) 12 weeks after the second injection of K45/20A vaccine. One of the three aborted at seven months' gestation (Brucella abortus culture positive), another had an SAT level of 100 iu 10 days after calving while the SAT titre of the third heifer continued to fall and remain negative after a normal calving. All the remaining heifers continued to give negative SAT. Recommendations are made for interpreting the anamnestic test for the diagnosis of the latent carrier state.
在272头接受了K45/20A疫苗单次注射后的布鲁氏菌病回忆性试验的小母牛中，53头（19%）抗牛球蛋白试验呈阳性，21头（8%）补体结合试验效价达到1/16或更高。在第二次注射K45/20A疫苗12周后，三头小母牛（1%）血清凝集试验（SAT）效价呈阳性（60国际单位或更高）。其中一头在妊娠七个月时流产（流产布鲁氏菌培养阳性），另一头在产犊后10天SAT水平为100国际单位，而第三头小母牛的SAT效价在正常产犊后持续下降并保持阴性。其余所有小母牛的SAT均持续呈阴性。针对用于诊断潜伏携带者状态的回忆性试验的解读提出了建议。
