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一种具有类似苯丙胺释放特性的巧茶树叶成分。

A constituent of khat leaves with amphetamine-like releasing properties.

作者信息

Kalix P

出版信息

Eur J Pharmacol. 1980 Nov 21;68(2):213-5. doi: 10.1016/0014-2999(80)90326-x.

DOI:10.1016/0014-2999(80)90326-x
PMID:7193583
Abstract

Khat leaves, which are widely abused as a stimulant, contain the alkaloid (--)-cathinone. The effect of this compound on the efflux of radioactivity from rabbit striatal tissue prelabelled with [3H]dopamine was examined. (--)-Cathinone enhanced the release of label, and was found to have a potency similar to that of (+)-amphetamine. The observation demonstrates that the khat alkaloid also has amphetamine-like effects at the cellular level.

摘要

作为兴奋剂被广泛滥用的巧茶树叶含有生物碱(--)-去甲伪麻黄碱。研究了该化合物对预先用[3H]多巴胺标记的兔纹状体组织中放射性流出的影响。(--)-去甲伪麻黄碱增强了标记物的释放,并且发现其效力与(+)-苯丙胺相似。该观察结果表明,巧茶生物碱在细胞水平上也具有类似苯丙胺的作用。

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A constituent of khat leaves with amphetamine-like releasing properties.一种具有类似苯丙胺释放特性的巧茶树叶成分。
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Cathinone, an alkaloid from khat leaves with an amphetamine-like releasing effect.卡西酮,一种来自巧茶树叶的生物碱,具有类似苯丙胺的释放效应。
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