Meinen K, Breinl H
Z Geburtshilfe Perinatol. 1980 Oct;184(5):339-42.
85 patients with premature labor were treated with the betamimetic drug Fenoterol over a period of 14 weeks. To rule out myocardial damage under the betaadrenergic therapy, the creatine kinase-isoenzyme-B serum level was measured via radioimmunoassay, next to ECG, CK-MB and serum myoglobin tests. Even with this highly sensitive and specific test which was applied for the first time in the perinatologic field, no myocardial necrosis was detectable. As the results of the CK-MB and the CK-B measurements correlate, this more elaborate examination should be reserved for selected cases.
85例早产患者接受了β-拟交感神经药物非诺特罗治疗，为期14周。为排除β-肾上腺素能治疗引起的心肌损伤，除进行心电图、肌酸激酶同工酶MB（CK-MB）和血清肌红蛋白检测外，还通过放射免疫分析法测定血清肌酸激酶同工酶B（CK-B）水平。即使采用了这种首次应用于围产医学领域的高灵敏度和特异性检测方法，也未检测到心肌坏死。由于CK-MB和CK-B测量结果具有相关性，这种更精细的检查应仅用于特定病例。
