8006-I, an antibiotic from Amblyosporium spongiosum (Pers.) Hughes sensu Pirozynski. I. Taxonomy, fermentation, isolation and physico-chemical properties.

A strain of Amblyosporium spongiosum (Pers.) Hughes sensu Pirozynski, HA 8006 isolated from an infected Lactarius deliciosus was found to produce two antibiotics, 8006-I and 8006-II. The same compounds could be isolated from cultures of several strains of the genus Amblyosporium obtained from the Centraalbureau voor Schimmelcultures. The highest yields of 8006-I (80 mg/liter culture) were obtained from the mycelium of strain HA 8006. Antibiotic 8006-I is unstable in the presence of light or oxygen and has a carotenoid structure.