Powers W J, Siegel B A, Davis H H, Mathias C J, Clark H B, Welch M J
Neurology. 1982 Sep;32(9):938-43. doi: 10.1212/wnl.32.9.938.
We obtained scintigraphic images of the neck from 100 patients with suspected cerebrovascular disease after injecting indium-111-labeled autologous platelets. One or more focuses of increased activity, implying local platelet accumulation, were seen along the course of the cervical carotid arteries in 52 patients. In 64 patients, there was a highly significant correlation between the results of scintigraphy and carotid arteriography (p = 10(6)). There was no significant correlation between the scintigraphic findings and the previous or subsequent occurrence of transient ischemic attack or cerebral infarction in the carotid circulation. These data suggest that factors other than the simple formation of platlet thrombi in the cervical carotid arteries are of primary importance in the pathogenesis of stroke.
我们对100例疑似脑血管疾病的患者注射铟-111标记的自体血小板后获得了颈部闪烁图像。52例患者在颈总动脉走行处可见一个或多个活性增强灶，提示局部血小板聚集。64例患者中，闪烁扫描结果与颈动脉造影结果之间存在高度显著相关性（p = 10⁻⁶）。闪烁扫描结果与颈动脉循环中既往或随后发生的短暂性脑缺血发作或脑梗死之间无显著相关性。这些数据表明，颈总动脉中单纯血小板血栓形成以外的因素在中风发病机制中起主要作用。
