精神分裂症患者血清素摄取与丙咪嗪结合之间的相关性。
Correlation between serotonin uptake and imipramine binding in schizophrenic patients.
作者信息
Rotman A, Shatz A, Szekely G A
出版信息
Prog Neuropsychopharmacol Biol Psychiatry. 1982;6(1):57-61. doi: 10.1016/s0364-7722(82)80108-2.
PMID:7202231
Abstract
- The active uptake of serotonin by platelets of schizophrenic patients and a healthy control group was compared with imipramine binding to these platelets. 2. Significant correlation was observed between the Vmax of serotonin uptake and the imipramine binding. 3. Serotonin uptake by patients was much lower than that of control group.
摘要
- 将精神分裂症患者和健康对照组血小板对血清素的主动摄取与这些血小板上丙咪嗪的结合情况进行了比较。2. 观察到血清素摄取的最大反应速度（Vmax）与丙咪嗪结合之间存在显著相关性。3. 患者的血清素摄取远低于对照组。
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