Tataryn I V, Lomax P, Bajorek J G, Chesarek W, Meldrum D R, Judd H L
Maturitas. 1980 Jul;2(2):101-7. doi: 10.1016/0378-5122(80)90043-2.
The changes in cutaneous and body temperature and cutaneous conductance during hot flushes in eight postmenopausal women were studied. The vasomotor changes occurred approx. 45 sec after the patients experienced the initial subjective symptoms of the attacks. The rise in skin conductance appeared to be a more reliable index of the flushing episode than did the change in skin temperature. On the basis of the changes recorded it is suggested that the hot flush syndrome may represent a specific thermoregulatory disorder rather than being due to a non-specific central autonomic discharge. The episodes may be triggered by a neuroendocrine imbalance following the disruption of ovarian function and fall in estrogen production. In assessing the frequency and severity of hot flushes, and the effects of treatment, objective measurements of skin and core temperature and skin conductance should replace subjective criteria.
对8名绝经后女性潮热期间的皮肤温度、体温及皮肤电传导变化进行了研究。血管舒缩变化大约在患者经历潮热发作的初始主观症状后45秒出现。与皮肤温度变化相比，皮肤电传导的升高似乎是潮热发作更可靠的指标。根据记录的变化情况，提示潮热综合征可能代表一种特定的体温调节障碍，而非由于非特异性的中枢自主神经放电所致。这些发作可能由卵巢功能破坏及雌激素分泌下降后出现的神经内分泌失衡所触发。在评估潮热的频率和严重程度以及治疗效果时，皮肤和核心体温以及皮肤电传导的客观测量应取代主观标准。
