Truhaut R, Anger J P, Anger F, Brault A, Brunet P, Cano Y, Louvet M, Saccavini J C, Van den Driessche J
Toxicol Eur Res. 1981 Jan;3(1):35-44.
Relative to an industrial application, the authors relate results obtained from a peculiar study on the thermic degradation of bis (tri-n-butyltin) oxide (TBTO) at various temperatures and they account for the toxic effects observed after inhaling the combustion products in the mouse and guinea pig. Thermolysis of TBTO between 200 and 600 degrees C gives saturated hydrocarbon and olefin gas, a condensate of tetrabutyltin and dibutyltin oxide and a residue composed of stannous or stannic oxides according to the temperature. Pulmonary toxicity is very important at low temperatures but after heating, toxic effects decrease. The results are confirmed by localisation and histopathologic studies. At 600 degrees C no death appears but some behavioral troubles occur. It's possible that repeated exposures can induce delayed toxicity.
相对于工业应用，作者阐述了在不同温度下对双（三正丁基锡）氧化物（TBTO）进行热降解的一项特殊研究所得出的结果，并说明了在小鼠和豚鼠吸入燃烧产物后观察到的毒性作用。在200至600摄氏度之间对TBTO进行热解，根据温度的不同会产生饱和烃和烯烃气体、四丁基锡和二丁基氧化锡的冷凝物以及由氧化亚锡或氧化锡组成的残留物。在低温下肺部毒性非常显著，但加热后毒性作用会降低。这些结果通过定位和组织病理学研究得到了证实。在600摄氏度时没有出现死亡情况，但会出现一些行为问题。反复接触有可能导致延迟性毒性。
