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母婴围产期样本中的有机氯农药浓度。

Organochlorine pesticide concentrations in perinatal samples from mothers and babies.

作者信息

Eckenhausen F W, Bennett D, Beynon K I, Elgar K E

出版信息

Arch Environ Health. 1981 Mar-Apr;36(2):81-92. doi: 10.1080/00039896.1981.10667611.

DOI:10.1080/00039896.1981.10667611
PMID:7212780
Abstract

Samples were obtained from Dutch mothers and their babies throughout the perinatal period and analyzed by gas-liquid chromatography with electron-capture detection for a range of organochlorine pesticides. Organochlorine concentrations in the blood of breast or bottle-fed babies were not significantly different. Differences in organochlorine concentrations in blood between mothers who had "slimmed" and those who had not were small, but it must be noted that there were few slimming mothers in our sample. Twelve to 21% and 36-61% of the estimated daily intake of dieldrin and DDT, respectively, by mothers may be eliminated by lactation. The placenta restricts the transmission of organochlorine pesticides to the fetus to some extent. The very low concentrations of organochlorine in fetal blood prevented a study of the comparative metabolism in mothers and babies.

摘要

在围产期从荷兰母亲及其婴儿身上采集样本,并通过带有电子捕获检测的气液色谱法对一系列有机氯农药进行分析。母乳喂养或奶瓶喂养婴儿血液中的有机氯浓度没有显著差异。“减肥”母亲和未“减肥”母亲血液中有机氯浓度的差异很小,但必须指出的是,我们的样本中减肥母亲很少。母亲摄入的狄氏剂和滴滴涕估计日摄入量分别有12%至21%和36%至61%可能通过哺乳排出。胎盘在一定程度上限制了有机氯农药向胎儿的传输。胎儿血液中极低的有机氯浓度使得无法对母亲和婴儿的比较代谢进行研究。

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