Ataullakhanov F I, Buravtsev V N, Vitvitsikiĭ V M, Dibrov B F, Zhabotinskiĭ A M
Biokhimiia. 1980 Jun;45(6):1075-9.
The behaviour of ATP concentrations in intact erythrocytes upon glucose addition to the erythrocyte suspension at a constant rate was studied. At different rates of glucose addition lower than the rate of glucose consumption at normalcy, the corresponding ATP concentrations are established, which are dependent on the rate of glucose influx. The 20% decrease of ATP concentration from the physiological value is observed at a 2-fold decrease of the flux. The results obtained made it possible to establish the dependence of the total rate of ATP consumption on ATP concentration in intact erythrocytes. This dependence is non-linear and shows a dramatic rise in the proximity of the physiological point.
研究了在红细胞悬液中以恒定速率添加葡萄糖时，完整红细胞中ATP浓度的变化情况。在低于正常葡萄糖消耗速率的不同葡萄糖添加速率下，会建立起相应的ATP浓度，该浓度取决于葡萄糖流入速率。当葡萄糖流入速率降低2倍时，观察到ATP浓度从生理值下降了20%。所得结果使得确定完整红细胞中ATP消耗总速率对ATP浓度的依赖性成为可能。这种依赖性是非线性的，并且在生理点附近呈现出急剧上升的趋势。
