Dimitriou P A, Karpathios T E, Antipas S E, Fretzayias A M, Kasfiki A G, Melissinos K G, Matsaniotis N S
Eur J Nucl Med. 1980 Oct;5(5):427-30. doi: 10.1007/BF00261786.
The plasma clearance rate of heat denatured human serum albumin (DHAI-125, 5 mg/kg body weight) was studied in 20 children with homozygous-beta-thalassemia before and 7--10 days after blood transfusion. A significant increase of the DHAI-125 clearance rate (P less than 0.02) was found 7--10 days after blood transfusion while the spleen presented its minimum size. This finding may be relevant to the improved intrasplenic blood circulation after blood transfusion due to the release of the blood trapped within the spleen.
在20名纯合子β地中海贫血患儿输血前及输血后7 - 10天，研究了热变性人血清白蛋白（DHAI - 125，5毫克/千克体重）的血浆清除率。输血后7 - 10天，当脾脏呈现最小尺寸时，发现DHAI - 125清除率显著增加（P小于0.02）。这一发现可能与输血后脾脏内血液循环改善有关，原因是被困在脾脏内的血液得以释放。
