Schnall R P, Landau L I
Thorax. 1980 Nov;35(11):828-32. doi: 10.1136/thx.35.11.828.
Many asthmatic patients demonstrate bronchial lability with a six-minute period of exercise, which is characterised by an initial bronchodilatation followed by bronchoconstriction. This early bronchodilatation response has been further analysed by investigation of the effects of repeated 30-second sprints before and after a six-minute run. It was found that these repeated short sprints did not induce bronchoconstriction, resulted in less bronchoconstriction after a subsequent six-minute run, and caused bronchodilatation if exercise-induced bronchoconstriction was present. It is postulated that this effect may be related to an increase in circulating catecholamines or altered vagal-sympathetic balance.
许多哮喘患者在进行六分钟运动时会表现出支气管易激性,其特征是最初支气管扩张,随后支气管收缩。通过研究在六分钟跑步前后重复进行30秒冲刺的效果,对这种早期支气管扩张反应进行了进一步分析。结果发现,这些重复的短距离冲刺不会诱发支气管收缩,在随后的六分钟跑步后导致的支气管收缩较少,并且如果存在运动诱发的支气管收缩,则会引起支气管扩张。据推测,这种效应可能与循环儿茶酚胺增加或迷走神经-交感神经平衡改变有关。