Powell C V, White R D, Primhak R A
University Department of Paediatrics, Children's Hospital, Sheffield.
Arch Dis Child. 1996 Feb;74(2):108-14. doi: 10.1136/adc.74.2.108.
The reproducibility of free running exercise challenge has been examined in an unselected population of 8-10 year olds. Using a standardised protocol, monthly exercise tests were performed on 143 children over one year. A positive test was defined using both a 15% and 20% fall in peak expiratory flow after exercise. The mean (95% confidence interval, CI) population frequency for a positive test at 15% fall was 14.9% (6.5 to 23.3) and coefficient of variation 24.6%. For a 20% fall, the mean (95% CI) population frequency was 7.9% (2.9 to 12.9) and coefficient of variation 27.8%. Seventy two (50.3%) of the children gave at least one positive response at 15% fall. Exercise testing is not reproducible in the community setting and should not be used as a screening test. Exercise data from epidemiological studies of asthma should be interpreted with caution.
在8至10岁未经过挑选的人群中对自由运动激发试验的可重复性进行了研究。采用标准化方案,在一年时间里对143名儿童进行了每月一次的运动测试。运动后呼气峰值流速下降15%和20%均被定义为阳性测试。运动后呼气峰值流速下降15%时,阳性测试的总体频率均值(95%置信区间,CI)为14.9%(6.5至23.3),变异系数为24.6%。运动后呼气峰值流速下降20%时,总体频率均值(95%CI)为7.9%(2.9至12.9),变异系数为27.8%。72名(50.3%)儿童在运动后呼气峰值流速下降15%时至少有一次阳性反应。在社区环境中运动测试不可重复,不应作为筛查测试使用。哮喘流行病学研究中的运动数据应谨慎解读。