Haughey R E, Lammers R L, Wagner D K
Ann Emerg Med. 1981 Apr;10(4):187-92. doi: 10.1016/s0196-0644(81)80159-x.
A prospective, randomized study was undertaken to determine the efficacy of prophylactic antibiotics in the treatment of various types of soft tissue hand wounds. A total of 394 patients were randomly assigned to one of two treatment groups, those receiving cephalexin (250 mg orally q.i.d. x 5 days), and the control group receiving no antibiotic. Patients were followed closely during the healing phase of their wounds. There was no statistical difference in the incidence of infection in the two groups.
开展了一项前瞻性随机研究，以确定预防性抗生素在治疗各种类型手部软组织伤口中的疗效。总共394例患者被随机分配到两个治疗组之一，一组接受头孢氨苄（口服250毫克，每日4次，共5天），对照组不使用抗生素。在伤口愈合阶段对患者进行密切随访。两组感染发生率无统计学差异。
