人铁蛋白的免疫学特性；对人血清铁蛋白测定的影响

Immunological characteristics of human ferritins; consequences for human serum ferritin determination.

作者信息

Mareschal J C, Dublet B, Wustefeld C, Charlier G, Crichton R R

出版信息

Clin Chim Acta. 1981 Mar 19;111(1):99-103. doi: 10.1016/0009-8981(81)90426-5.

Abstract

Standard curves established with human spleen, liver, placenta and heart ferritins for eight commercial radioimmunological procedures show that liver and spleen ferritins present almost identical responses, whereas three times as much placenta ferritin and six times as much heart ferritin were required to give the same response as liver and spleen ferritins. There are great variations between the kits in the estimation of the ferritin level of a control serum.

摘要

用人类脾脏、肝脏、胎盘和心脏铁蛋白为8种商业放射免疫测定法建立的标准曲线表明，肝脏和脾脏铁蛋白呈现几乎相同的反应，而要产生与肝脏和脾脏铁蛋白相同的反应，胎盘铁蛋白的用量需为其三倍，心脏铁蛋白的用量需为其六倍。在对照血清铁蛋白水平的测定中，各试剂盒之间存在很大差异。