Palmer D G, Hale G M, Grennan D M, Pollock M
J Rheumatol. 1981 Mar-Apr;8(2):266-72.
Thirteen patients who had in common the clinical finding of shortened forearm flexors were investigated. Additional findings were Raynaud's phenomenon, arthralgia, reduced pulmonary CO diffusion capacity, abnormal EMG, and histological evidence of myopathy. Clinical and serological features in 2 patients were consistent with features described in the mixed connective tissue disease syndrome. The remainder were regarded as having a limited connective tissue disease syndrome, in all probability, a minimal expression of systemic sclerosis. We suggest that the finding of bowed fingers is a more reliable clinical sign than the assessment of skin texture in determining the presence of minimal connective tissue disease.
对13例有共同临床表现即前臂屈肌缩短的患者进行了研究。其他表现包括雷诺现象、关节痛、肺一氧化碳弥散能力降低、肌电图异常以及肌病的组织学证据。2例患者的临床和血清学特征与混合性结缔组织病综合征中描述的特征一致。其余患者被认为患有局限性结缔组织病综合征,很可能是系统性硬化症的一种轻微表现。我们认为,在确定是否存在轻微结缔组织病时,手指弯曲的表现比皮肤质地评估是更可靠的临床体征。