Scott D L, Delamere J P, Mackintosh L P, Jobson S
Rheumatol Int. 1982;2(3):141-3. doi: 10.1007/BF00541168.
Cheiroarthropathy is a recently recognised complication of juvenile onset diabetes mellitus. It comprises inability to extend fully the fingers, contracted tendons, and waxy thickening of the skin overlying the fingers and to a lesser extent the hands. We report two families in which one parent and a number of siblings had the typical features of cheiroarthropathy without juvenile onset diabetes mellitus. The changes developed gradually during childhood and did not progress after adolescence. There were no other abnormal clinical findings, no persistently abnormal laboratory tests, and no association with a specific HLA phenotype. There are some similarities with scleroderma and its recognition is important to prevent unnecessary treatment and to reassure patients.
手部关节病是青少年期糖尿病最近才被认识到的一种并发症。它表现为手指无法完全伸直、肌腱挛缩以及手指及程度较轻的手部皮肤蜡样增厚。我们报告了两个家族，其中一位家长和多个兄弟姐妹有手部关节病的典型特征，但没有青少年期糖尿病。这些改变在儿童期逐渐发展，青春期后不再进展。没有其他异常临床发现，实验室检查也没有持续异常，且与特定的人类白细胞抗原（HLA）表型无关。它与硬皮病有一些相似之处，认识到这一点对于避免不必要的治疗和安抚患者很重要。
