Roncari D A, Lau D C, Kindler S
Metabolism. 1981 May;30(5):425-7. doi: 10.1016/0026-0495(81)90174-8.
The characteristics of omental adipocyte precursors from massively obese patients, whose average body weights were 231% (range 70--369) of reference values, were studied in propagating culture. When compared to cells from lean subjects, the adipocyte precursors from 34 massively obese patients replicated at a significantly higher rate (p less than 0.001). Excessive replication persisted throughout the first five subcultures. Thus, this characteristic is inherent in the cells, and may reflect the operation of genetic factors in this subgroup of the obese population.
对平均体重为参考值231%（范围70 - 369）的极度肥胖患者的网膜脂肪细胞前体特征进行了传代培养研究。与瘦人来源的细胞相比，34名极度肥胖患者的脂肪细胞前体复制速度明显更快（p < 0.001）。在前五次传代培养中，过度复制现象一直存在。因此，这一特征是细胞所固有的，可能反映了该肥胖人群亚组中遗传因素的作用。
