Taylor C R, Weibel E R
Respir Physiol. 1981 Apr;44(1):1-10.
This paper introduces a series of reports on the structure and function of the respiratory system of mammals. We propose and justify the hypothesis that structural design is a limiting factor for O2 flow at each level of the respiratory system. The background, the reasons, and the plan for the studies are described. The main approach is to compare the size of respiratory structures with maximal O2 consumption in a series of mammals spanning several orders of magnitude in body size. The papers that follow present the methods and results for maximal O2 consumption, pulmonary diffusing capacity, mitochondrial volume, and capillary density in muscles.
本文介绍了一系列关于哺乳动物呼吸系统结构和功能的报告。我们提出并论证了以下假设：在呼吸系统的每个层面，结构设计都是氧气流动的限制因素。文中描述了研究的背景、原因和计划。主要方法是在一系列体型跨越几个数量级的哺乳动物中，比较呼吸结构的大小与最大耗氧量。后续论文介绍了最大耗氧量、肺扩散能力、线粒体体积和肌肉毛细血管密度的测量方法及结果。
