用肌苷对缺血犬肾进行保存。
Preservation of the ischaemic canine kidney with inosine.
作者信息
Rothwell D, Bartley J, James M
出版信息
Urol Res. 1981;9(2):75-8. doi: 10.1007/BF00256680.
PMID:7233650
Abstract
Direct intra-renal perfusion of inosine was found to protect the canine kidney from 90 min of warm ischaemia. Significantly lower (P less than 0.01) serum creatinine levels were found 24 and 72 h post-operatively in an inosine treated group (N = 12) when compared to a control group (N = 5). Histological examination of the pre-treated kidneys confirmed the protective effect of inosine.
摘要
研究发现，直接向犬肾内灌注肌苷可保护犬肾免受90分钟的热缺血损伤。与对照组（N = 5）相比，肌苷治疗组（N = 12）术后24小时和72小时的血清肌酐水平显著降低（P < 0.01）。对预处理肾脏的组织学检查证实了肌苷的保护作用。
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