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工作与休闲时的体力活动与冠心病危险因素及社会阶层的关系。一项为期4年的死亡率随访研究。奥斯陆研究。

Physical activity at work and at leisure in relation to coronary risk factors and social class. A 4-year mortality follow-up. The Oslo study.

作者信息

Holme I, Helgeland A, Hjermann I, Leren P, Lund-Larsen P G

出版信息

Acta Med Scand. 1981;209(4):277-83. doi: 10.1111/j.0954-6820.1981.tb11591.x.

Abstract

The association between physical activity at work and at leisure, coronary risk factors, social class and mortality has been studied in about 15000 Oslo men, aged 40-49, without known cardiovascular disease or diabetes at a screening examination for coronary risk factors. Four-year total and CHD mortality showed a decrease with increasing degree of leisure activity, and an increase with increasing work activity. The three conventional coronary risk factors--serum cholesterol, systolic blood pressure (SBP) and number of cigarettes--associated negatively with physical leisure activity, whereas they all associated positively with physical activity at work. Men in lower social classes were less active at leisure but more active at work than men in the higher classes. In a multivariate analysis of variance with coronary risk score (based on SBP, serum total cholesterol and number of cigarettes), social class and physical activity, the predictive power of physical leisure activity for future death was almost as good as the coronary risk score. Physical activity at work, on the other hand, was not an independent risk factor either for total or for CHD mortality.

摘要

在一项针对约15000名40至49岁奥斯陆男性的研究中,探讨了工作和休闲时的体力活动与冠心病危险因素、社会阶层及死亡率之间的关联。这些男性在冠心病危险因素筛查时并无已知的心血管疾病或糖尿病。四年的全因死亡率和冠心病死亡率显示,休闲活动程度增加时死亡率降低,而工作活动增加时死亡率升高。三种传统的冠心病危险因素——血清胆固醇、收缩压(SBP)和吸烟量——与休闲体力活动呈负相关,而它们均与工作时的体力活动呈正相关。社会阶层较低的男性在休闲时活动较少,但在工作时比社会阶层较高的男性更活跃。在一项对冠心病风险评分(基于SBP、血清总胆固醇和吸烟量)、社会阶层和体力活动进行的多变量方差分析中,休闲体力活动对未来死亡的预测能力几乎与冠心病风险评分相当。另一方面,工作时的体力活动无论是对全因死亡率还是冠心病死亡率而言,都不是一个独立的危险因素。

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