Thune I, Lund E
Norwegian Cancer Society, University of Tromsø.
Cancer Causes Control. 1994 Nov;5(6):549-56. doi: 10.1007/BF01831383.
The associations between recreational and occupational physical activity and the subsequent risk of prostate and testicular cancer were examined in a population-based cohort study of 53,242 men in Norway. Age at study entry was 19 to 50 years. Information on physical activity was based on questionnaire responses and a brief clinical examination. A total of 220 prostate and 47 testicular cancer cases were recorded in the Cancer Registry of Norway during a mean follow-up time of 16.3 years. We found a nonsignificant, reduced, adjusted relative risk (RR) of prostate cancer with increased level of physical activity at work and among those men with the greatest recreational physical activity. When occupational and recreational physical activity were combined, a reduced adjusted risk of prostate cancer was observed among men who walked during occupational hours and performed either moderate recreational activity (RR = 0.61, 95 percent confidence interval [CI] = 0.36 to 1.01) or regular recreational training (RR = 0.45, CI = 0.20 to 1.01) relative to sedentary men (test for trend, P = 0.03). Physically active men who were older than 60 years of age at diagnosis showed a reduced adjusted RR of borderline significance, while no association was observed for younger men. No evidence was found for any association between physical activity and testicular cancer regardless of physical activity at work and recreation.
在挪威一项针对53242名男性的基于人群的队列研究中，研究了娱乐性和职业性体育活动与随后患前列腺癌和睾丸癌风险之间的关联。研究开始时的年龄为19至50岁。体育活动信息基于问卷调查回复和简短的临床检查。在平均16.3年的随访期内，挪威癌症登记处共记录了220例前列腺癌和47例睾丸癌病例。我们发现，工作时体育活动水平增加以及娱乐性体育活动量最大的男性中，前列腺癌的调整后相对风险（RR）有所降低，但差异无统计学意义。当将职业性和娱乐性体育活动结合起来时，相对于久坐不动的男性，在工作时间步行且进行适度娱乐活动（RR = 0.61，95%置信区间[CI] = 0.36至1.01）或定期娱乐训练（RR = 0.45，CI = 0.20至1.01）的男性中，观察到前列腺癌的调整后风险降低（趋势检验，P = 0.03）。诊断时年龄大于60岁的体力活动男性的调整后RR降低，具有临界显著性，而年轻男性未观察到关联。无论工作和娱乐时的体育活动情况如何，均未发现体育活动与睾丸癌之间存在任何关联的证据。
