Bradley S L, Pairolero P C, Payne W S, Gracey D R
Arch Surg. 1981 Jun;116(6):755-8. doi: 10.1001/archsurg.1981.01380180017004.
The records of all patients with spontaneous esophageal perforations who were examined between August 1966 and December 1978 were reviewed. Eleven patients (six men and five women) whose mean age was 62.8 years were treated during this period. Precipitating factors that contributed to perforation were identified in all patients. Ten patients had epigastric or low sternal pain. Chest roentgenograms were abnormal for all patients. Two patients were treated conservatively, and both died. Of the nine patients treated by thoracotomy, the two who were treated within 24 hours of perforation survived. Of the seven patients treated later than 24 hours, only three survived. Late treatment consisted of either primary closure or esophageal exclusion. Prompt surgical intervention remains the treatment of choice.
回顾了1966年8月至1978年12月期间所有接受检查的自发性食管穿孔患者的记录。在此期间治疗了11例患者（6例男性和5例女性），平均年龄为62.8岁。所有患者均确定了促成穿孔的诱发因素。10例患者有上腹部或胸骨下部疼痛。所有患者的胸部X线片均异常。2例患者接受保守治疗，均死亡。在接受开胸手术治疗的9例患者中，穿孔后24小时内接受治疗的2例存活。在穿孔后24小时后接受治疗的7例患者中，只有3例存活。后期治疗包括一期缝合或食管旷置。及时的手术干预仍然是首选的治疗方法。
