Gorsky J E, Dietz A A
Clin Chem. 1981 Jun;27(6):932-5.
Aluminum has been implicated in the etiology of the progressive dialytic encephalopathy. Data are presented on samples taken from patients on maintenance hemodialysis, during treatment. Aluminum was determined by electrothermal atomic absorption spectroscopy. Hemodialysis had no significant effect on serum aluminum concentrations, which ranged from 27 to 254 micrograms of Al per liter (1.00 to 9.42 mumol/L). Isolated ultrafiltration removed part of the serum aluminum, but most remained bound to a nonfiltrable component. These results are evaluated in the light of present knowledge concerning dialysis dementia.
铝已被认为与进行性透析性脑病的病因有关。本文给出了在维持性血液透析治疗期间从患者身上采集的样本数据。通过电热原子吸收光谱法测定铝含量。血液透析对血清铝浓度没有显著影响,血清铝浓度范围为每升27至254微克铝(1.00至9.42微摩尔/升)。单纯超滤去除了部分血清铝,但大部分仍与不可滤过成分结合。根据目前关于透析性痴呆的知识对这些结果进行了评估。