Waters M D, Auletta A
J Chem Inf Comput Sci. 1981 Feb;21(1):35-8. doi: 10.1021/ci00029a007.
The GENE-TOX program, a two-phase evaluation from the existing literature of selected bioassays for detecting mutagenicity and presumptive carcinogenicity, is described. Sponsored and directed by the Office of Testing and Evaluation within the U.S. Environmental Protection Agency's (EPA) Office of Pesticides and Toxic Substances, this program will aid EPA in establishing standard genetic testing and evaluation procedures for the regulation of toxic substances and determining the direction of research and development in the area of genetic toxicology.
本文介绍了基因毒性计划（GENE-TOX），这是一项对用于检测致突变性和推定致癌性的选定生物测定法进行两阶段文献评估的计划。该计划由美国环境保护局（EPA）农药和有毒物质办公室的测试与评估办公室发起并指导，将协助EPA建立用于监管有毒物质的标准基因检测和评估程序，并确定基因毒理学领域的研发方向。
