Eshaghian J, Goeken J A
Ophthalmology. 1980 Nov;87(11):1160-6. doi: 10.1016/s0161-6420(80)35110-5.
A controlled study of C-reactive protein in patients with and without temporal arteritis was performed. C-reactive protein was elevated in 10 of 11 patients with biopsy-proven temporal arteritis before treatment. It was positive in 14 of 32 control patients with negative temporal artery biopsies. This difference is statistically significant. C-reactive protein was elevated in 6 to 9 (depending on the adequacy of therapy) of 34 patients with temporal arteritis after corticosteroids were started. C-reactive protein and erythrocyte sedimentation rate are positively correlated in untreated arteritis. Clinical correlation showed C-reactive protein was more sensitive than the erythrocyte sedimentation rate in following the adequacy of corticosteroid dosages in temporal arteritis probably because many more noninflammatory factors influence erythrocyte sedimentation than influence C-reactive protein.
对患有和未患颞动脉炎的患者进行了C反应蛋白的对照研究。在11例经活检证实的颞动脉炎患者中，有10例在治疗前C反应蛋白升高。在32例颞动脉活检阴性的对照患者中，有14例呈阳性。这种差异具有统计学意义。在开始使用皮质类固醇后，34例颞动脉炎患者中有6至9例（取决于治疗的充分性）C反应蛋白升高。在未经治疗的动脉炎中，C反应蛋白与红细胞沉降率呈正相关。临床相关性表明，在跟踪颞动脉炎中皮质类固醇剂量的充分性方面，C反应蛋白比红细胞沉降率更敏感，这可能是因为影响红细胞沉降的非炎症因素比影响C反应蛋白的更多。
