血小板指数和中性粒细胞与淋巴细胞比值能否成为区分动脉炎性前部缺血性视神经病变与非动脉炎性类型的新生物标志物？
Could Platelet Indices and Neutrophil to Lymphocyte Ratio Be New Biomarkers for Differentiation of Arteritic Anterior Ischemic Neuropathy from Non-Arteritic Type?
作者信息
Inanc Merve, Tekin Kemal, Budakoglu Ozlem, Ilhan Bayazit, Aydemir Onder, Yilmazbas Pelin
机构信息
Ankara Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.
Kars State Hospital, Kars, Turkey.
出版信息
Neuroophthalmology. 2018 Jan 9;42(5):287-294. doi: 10.1080/01658107.2017.1405995. eCollection 2018 Oct.
Abstract
The aim of this study was to assess the possible relationship between AAION (arteritic anterior ischemic optic neuropathy) and NAION (non-arteritic anterior ischemic optic neuropathy) with blood platelet parameters and NLR (neutrophil-to-lymphocyte ratio). The medical records of 12 patients with AAION, 33 patients with NAION, and 35 healthy subjects were examined. MPV, PDW, and PCT values showed marked elevation in AAION and NAION groups compared with control group. The mean NLR was statistically significantly higher only in AAION group compared to the NAION and control groups, suggesting that platelet function plays an important role in AIONs and NLR might be used to differentiate AAION from NAION.
摘要
本研究旨在评估动脉炎性前部缺血性视神经病变（AAION）和非动脉炎性前部缺血性视神经病变（NAION）与血小板参数及中性粒细胞与淋巴细胞比值（NLR）之间的可能关系。对12例AAION患者、33例NAION患者和35例健康受试者的病历进行了检查。与对照组相比，AAION组和NAION组的平均血小板体积（MPV）、血小板分布宽度（PDW）和血小板压积（PCT）值显著升高。与NAION组和对照组相比，仅AAION组的平均NLR在统计学上显著更高，这表明血小板功能在前部缺血性视神经病变（AION）中起重要作用，且NLR可能用于区分AAION和NAION。
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