Gerstle C C, Friedman A H
Ophthalmology. 1980 Nov;87(11):1173-6. doi: 10.1016/s0161-6420(80)35109-9.
A 68-year-old white woman was seen because of pain in each eye associated with the development of a marginal corneal ulceration (limbal guttering) bilaterally. Subsequently, the patient developed swelling over the bridge of the nose, painful necrotic lesions of the fingernail beds, scalp, on one knee, and conjunctival ulceration with scleral thinning. Medical examination revealed a markedly elevated erythrocyte sedimentation rate. A temporal artery biopsy specimen was positive for giant cell arteritis. The skin and ocular lesions resolved when the patient was given systemic corticosteroid therapy. The systemic and ocular manifestations of giant cell arteritis and the differential diagnosis and cause of limbal guttering are discussed.
一名68岁的白人女性因双眼疼痛并伴有双侧边缘角膜溃疡（角膜缘沟）而前来就诊。随后，患者鼻梁处出现肿胀，甲床、头皮、一侧膝盖出现疼痛性坏死性病变，结膜溃疡并伴有巩膜变薄。医学检查显示红细胞沉降率显著升高。颞动脉活检标本巨细胞动脉炎呈阳性。给予患者全身皮质类固醇治疗后，皮肤和眼部病变消退。本文讨论了巨细胞动脉炎的全身和眼部表现以及角膜缘沟的鉴别诊断和病因。
