Pösö A R, Hillbom M E, Eriksson L
Toxicol Lett. 1981 Apr;8(1-2):57-62. doi: 10.1016/0378-4274(81)90138-7.
Goats received ethanol or acetaldehyde via carotid arterial infusions. Cerebrospinal fluid (CSF) was sampled for a lateral cerebral ventricle and blood from a jugular vein. Ethanol infusions produced only negligible levels of acetaldehyde in blood and CSF, but acetaldehyde infusions resulted in high levels. In contrast to ethanol, acetaldehyde was rapidly eliminated from both blood and CSF after discontinuing the infusion. The results indicate that even small amounts of acetaldehyde easily penetrate the blood-liquor barrier of goats.
山羊通过颈动脉输注接受乙醇或乙醛。采集大脑侧脑室的脑脊液（CSF）以及颈静脉血。乙醇输注在血液和脑脊液中仅产生可忽略不计的乙醛水平，但乙醛输注导致高水平的乙醛。与乙醇不同，停止输注后，乙醛能迅速从血液和脑脊液中清除。结果表明，即使少量的乙醛也能轻易穿透山羊的血脑屏障。
