• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

In vivo acetaldehyde in the brain of the rat treated with ethanol.

作者信息

Westcott J Y, Weiner H, Shultz J, Myers R D

出版信息

Biochem Pharmacol. 1980 Feb;29(3):411-7. doi: 10.1016/0006-2952(80)90521-3.

DOI:10.1016/0006-2952(80)90521-3
PMID:7362655
Abstract
摘要

相似文献

1
In vivo acetaldehyde in the brain of the rat treated with ethanol.用乙醇处理的大鼠大脑中的体内乙醛。
Biochem Pharmacol. 1980 Feb;29(3):411-7. doi: 10.1016/0006-2952(80)90521-3.
2
Disulfiram as a tool in the studies on the metabolism of acetaldehyde in rats.双硫仑作为研究大鼠乙醛代谢的工具。
Acta Pharmacol Toxicol (Copenh). 1976 Apr;38(4):366-75. doi: 10.1111/j.1600-0773.1976.tb03132.x.
3
Inactivation of coenzyme a by ethanol. I. Acetaldehyde as mediator of the inactivation of coenzyme A following the administration of ethanol in vivo.乙醇对辅酶A的失活作用。I. 体内给予乙醇后，乙醛作为辅酶A失活的介导物
Biochem Pharmacol. 1969 Jan;18(1):29-33. doi: 10.1016/0006-2952(69)90005-7.
4
The acetaldehyde content in rat brain during ethanol metabolism.
J Neurochem. 1974 Aug;23(2):451-2. doi: 10.1111/j.1471-4159.1974.tb04380.x.
5
On the disulfiram-like activity of moxalactam.
Clin Pharmacol Ther. 1982 Sep;32(3):347-55. doi: 10.1038/clpt.1982.170.
6
Acetaldehyde accumulation suppresses Kupffer cell release of TNF-Alpha and modifies acute hepatic inflammation in rats.乙醛蓄积抑制大鼠库普弗细胞释放肿瘤坏死因子-α并改变急性肝脏炎症。
J Gastroenterol. 2004;39(2):140-7. doi: 10.1007/s00535-003-1278-5.
7
Increased Brain Serotonin Rather Than Increased Blood Acetaldehyde as a Common Denominator Behind Alleged Disulfiram-Like Reactions.
Int J Toxicol. 2020 May/Jun;39(3):248-255. doi: 10.1177/1091581820918169. Epub 2020 Apr 15.
8
The distribution and metabolism of acetaldehyde in rats during ethanol oxidation-I. The distribution of acetaldehyde in liver, brain, blood and breath.乙醇氧化过程中大鼠体内乙醛的分布与代谢——I. 乙醛在肝脏、大脑、血液和呼出气体中的分布
Biochem Pharmacol. 1977 Feb 1;26(3):241-7. doi: 10.1016/0006-2952(77)90310-0.
9
Influence of disulfiram (antabuse, TETD) on the metabolism of radioactive CH3C14H2OH and acetaldehyde in mice.双硫仑（戒酒硫、四乙基秋兰姆化二硫）对小鼠体内放射性CH3C14H2OH和乙醛代谢的影响。
Arch Int Pharmacodyn Ther. 1956 Jul 1;107(1):109-11.
10
Pharmaceutical agents known to produce disulfiram-like reaction: effects on hepatic ethanol metabolism and brain monoamines.已知可产生双硫仑样反应的药物制剂：对肝脏乙醇代谢和脑单胺的影响。
Int J Toxicol. 2007 Sep-Oct;26(5):423-32. doi: 10.1080/10915810701583010.

引用本文的文献

1
Sex- and ALDH2-dependent differences in alcohol metabolism and psychomotor performance: a study in Han Chinese adults after binge drinking.饮酒代谢及精神运动表现中性别及乙醛脱氢酶2依赖性差异：对汉族成年人暴饮后情况的一项研究
Ann Med. 2025 Dec;57(1):2496798. doi: 10.1080/07853890.2025.2496798. Epub 2025 Apr 28.
2
Coordinated action of a gut-liver pathway drives alcohol detoxification and consumption.肠道-肝脏途径的协调作用驱动酒精解毒和摄入。
Nat Metab. 2024 Jul;6(7):1380-1396. doi: 10.1038/s42255-024-01063-2. Epub 2024 Jun 20.
3
Role of Acetaldehyde in Ethanol Reversal of Tolerance to Morphine-Induced Respiratory Depression in Mice.
乙醛在乙醇逆转小鼠对吗啡诱导的呼吸抑制耐受性中的作用。
Adv Drug Alcohol Res. 2022 Jan 31;1. doi: 10.3389/adar.2021.10143.
4
Acetaldehyde Excitation of Lateral Habenular Neurons via Multiple Cellular Mechanisms.乙醛通过多种细胞机制激发外侧缰核神经元。
J Neurosci. 2021 Sep 8;41(36):7532-7545. doi: 10.1523/JNEUROSCI.2913-20.2021. Epub 2021 Jul 29.
5
The Role of Alcohol Metabolism in the Pathology of Alcohol Hangover.酒精代谢在酒精宿醉病理学中的作用。
J Clin Med. 2020 Oct 25;9(11):3421. doi: 10.3390/jcm9113421.
6
Salsolinol: an Unintelligible and Double-Faced Molecule-Lessons Learned from In Vivo and In Vitro Experiments.索洛辛醇：一种难以理解且具有双重面孔的分子——体内和体外实验的教训。
Neurotox Res. 2018 Feb;33(2):485-514. doi: 10.1007/s12640-017-9818-6. Epub 2017 Oct 23.
7
Mystic Acetaldehyde: The Never-Ending Story on Alcoholism.神秘的乙醛：关于酗酒的无尽故事
Front Behav Neurosci. 2017 May 11;11:81. doi: 10.3389/fnbeh.2017.00081. eCollection 2017.
8
Altering ethanol pharmacokinetics to treat alcohol use disorder: Can you teach an old dog new tricks?改变乙醇药代动力学以治疗酒精使用障碍：老狗能学新把戏吗？
J Psychopharmacol. 2017 Jul;31(7):812-818. doi: 10.1177/0269881116684338. Epub 2017 Jan 16.
9
From Ethanol to Salsolinol: Role of Ethanol Metabolites in the Effects of Ethanol.从乙醇到萨索林醇：乙醇代谢产物在乙醇效应中的作用
J Exp Neurosci. 2016 Nov 20;10:137-146. doi: 10.4137/JEN.S25099. eCollection 2016.
10
Ethanol and Acetaldehyde After Intraperitoneal Administration to Aldh2-Knockout Mice-Reflection in Blood and Brain Levels.腹腔注射乙醇和乙醛至醛脱氢酶2基因敲除小鼠后——血液和脑内水平反映
Neurochem Res. 2016 May;41(5):1029-34. doi: 10.1007/s11064-015-1788-6. Epub 2015 Dec 8.