Aoki H, Inaba N, Ohkawa R, Kudoh J, Takamizawa H
Acta Obstet Gynaecol Jpn. 1981 Jun;33(6):767-76.
In order to assess the possible sexual transmission of hepatitis B virus (HBV), the occurrence of post-marital acute hepatitis and the prevalence of hepatitis B surface antigen (HBsAg) and antibody (HBsAb) were investigated among the husbands of HBsAg carrier women. The possible infectious routes and influencing factors in the HBV infection of the husbands by their HBsAg carrier wives were also discussed. This study demonstrates: 1. In the husbands examined, the exposure marker of HBV was found to be 32.8 per cent and the occurrence rate of post-marital hepatitis came up to 7.2 per cent. 2. The transmission of HBV from HBsAg carrier women to their husbands was supposed to take place shortly after marriage. E-Ag and e-Ab in ther sera of HBsAg carrier women could serve respectively as indicators of positive and negative HBV transmission. In the husbands with wives whose serum HBsAg-titers by R-PHA were higher than 39, a high exposure marker of HBV (87.5%) was observed. 3. The results of HBsAg detection rates and titers in various kinds of body fluids obtained from HBsAg carrier women suggested that cervical mucus and vaginal discharge might play an important role in the sexual HBV transmission.
为了评估乙型肝炎病毒（HBV）可能的性传播情况，对HBsAg携带者女性的丈夫进行了婚后急性肝炎发生率以及乙肝表面抗原（HBsAg）和抗体（HBsAb）患病率的调查。还讨论了HBsAg携带者妻子将HBV传染给丈夫的可能感染途径及影响因素。本研究表明：1. 在接受检查的丈夫中，HBV暴露标志物检出率为32.8%，婚后肝炎发生率达7.2%。2. HBV从HBsAg携带者女性传给其丈夫的情况推测发生在婚后不久。HBsAg携带者女性血清中的E抗原和E抗体可分别作为HBV传播阳性和阴性的指标。在其妻子R-PHA法检测血清HBsAg滴度高于39的丈夫中，观察到较高的HBV暴露标志物检出率（87.5%）。3. 对HBsAg携带者女性各种体液的HBsAg检出率和滴度检测结果表明，宫颈黏液和阴道分泌物可能在HBV性传播中起重要作用。
