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控制心血管疾病的风险因素。

Controlling risk factors in cardiovascular diseases.

作者信息

Tuomilehto J, Puska P, Salonen J, Nissinen A

出版信息

Ann Acad Med Singap. 1980 Oct;9(4):446-55.

PMID:7247330
Abstract

In response to community demands to do something about the highest rates of cardiovascular diseases in the world that were found in the country of North Karelia, Finland, a comprehensive community control programme was set up in 1972. The main objective was to reduce the high rates by reducing level of smoking, serum cholesterol and blood pressure. The success of the programme was evaluated by examining independent representative population samples in 1972 and in 1977 in North Karelia and a matched control county. A decrease in the individual risk factors was found among the population aged 25-29 at the outset. This reduction was mainly based on favourable changes in lifestyle that took place through the whole community. In low as well as in high socioeconomic groups risk factor reductions occurred. At the same time morbidity and mortality from cardiovascular diseases fell in North Karelia. The intensified health education was not accompanied by adverse emotional or psychosomatic reactions that could be measured. Since there are results from a series of experimental and controlled studies on success of risk factor reduction, this evidence should be used in development and implementation of prevention programmes for cardiovascular diseases. Primary prevention of cardiovascular diseases today requires efficient programmes because they are forming the leading cause of death in majority of the countries where reliable mortality statistics are available.

摘要

为回应社会要求针对芬兰北卡累利阿地区发现的世界最高心血管疾病发病率采取行动的呼声,1972年设立了一项全面的社区控制计划。主要目标是通过降低吸烟率、血清胆固醇水平和血压来降低高发病率。该计划的成功通过在1972年和1977年对北卡累利阿地区以及一个匹配的对照县的独立代表性人群样本进行检查来评估。在开始时,25至29岁人群中的个体风险因素有所下降。这种下降主要基于整个社区生活方式的有利变化。在低社会经济群体和高社会经济群体中都出现了风险因素的降低。与此同时,北卡累利阿地区心血管疾病的发病率和死亡率下降。强化的健康教育并未伴随着可测量的不良情绪或心身反应。由于有一系列关于降低风险因素成功的实验性和对照研究的结果,这些证据应用于心血管疾病预防计划的制定和实施。如今,心血管疾病的一级预防需要有效的计划,因为在大多数有可靠死亡率统计数据的国家,心血管疾病是主要死因。

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