Marcus J, Auerbach J, Wilkinson L, Burack C M
Arch Gen Psychiatry. 1981 Jun;38(6):703-13. doi: 10.1001/archpsyc.1981.01780310103011.
The development of infants born to parents with serious mental disorders was followed up from birth through the first year of life. An individual-differences approach to statistical analysis. Multidimensional Scalogram Analysis (MSA), was shown to be an effective statistical procedure for examining heterogeneous psychiatric populations. The MSA revealed the existence of a subgroup of infants born to schizophrenics who repeatedly performed poorly in motor and sensorimotor areas of functioning during their first year of life. These infants were especially vulnerable to external insults, and many had low to low-normal birth weights. These findings, taken together with similar findings from other investigations, add support to the hypothesis that these infants may have a genetically determined neurointegrative deficit.
对父母患有严重精神障碍的婴儿从出生到一岁进行了追踪研究。采用了个体差异的统计分析方法，即多维量表分析（MSA），结果表明这是一种检验异质性精神疾病群体的有效统计程序。MSA显示，精神分裂症患者所生的婴儿中有一个亚组，这些婴儿在出生后的第一年里，在运动和感觉运动功能领域的表现反复不佳。这些婴儿特别容易受到外部伤害，而且许多婴儿出生体重偏低至正常低限。这些发现，连同其他调查的类似结果，为这些婴儿可能存在基因决定的神经整合缺陷这一假说提供了支持。
