Laghi V, Cauda R, Nervo P
Arch Sci Med (Torino). 1980 Oct-Dec;137(4):575-7.
The lymphocytotoxicity to rabbit hepatocytes either direct or serum induced was evaluated in chronic active hepatitis (CAH). We obtained the following results: a) the direct lymphocytotoxicity obtained in CAH patients significantly correlated with the cytotoxicity induced by CAH sera in normal lymphocytes; b) no difference could be recorded in CAH HBsAG positive or negative; c) the target antigen of the immune reaction seems to be the liver specific lipoprotein.
在慢性活动性肝炎（CAH）中评估了对兔肝细胞的淋巴细胞毒性，包括直接的和血清诱导的淋巴细胞毒性。我们得到了以下结果：a）CAH患者中获得的直接淋巴细胞毒性与CAH血清在正常淋巴细胞中诱导的细胞毒性显著相关；b）CAH乙肝表面抗原（HBsAG）阳性或阴性患者之间未记录到差异；c）免疫反应的靶抗原似乎是肝脏特异性脂蛋白。
