蝾螈眼后节的组蛋白基因簇被长片段的卫星DNA分隔开。

Histone gene clusters of the newt notophthalmus are separated by long tracts of satellite DNA.

作者信息

Stephenson E C, Erba H P, Gall J G

出版信息

Cell. 1981 Jun;24(3):639-47. doi: 10.1016/0092-8674(81)90090-8.

Abstract

The genomic organization of the histone genes of the newt Notophthalmus viridescens is described. Genes for the five proteins are clustered on a 9.0 kb segment of cloned DNA which is part of a homogeneous family of sequences containing 600--800 members per haploid genome. The 9.0 kb histone gene clusters are not adjacent in the genome, but are separated from neighboring clusters by up to 50 kb or more of cluster spacer sequences; some or all of these spacer sequences are members of a predominantly centromeric satellite DNA with a 2235 bp repeating unit.

摘要

本文描述了蝾螈绿红东美螈组蛋白基因的基因组组织。这五种蛋白质的基因聚集在一段9.0 kb的克隆DNA片段上，该片段是一个同源序列家族的一部分，每个单倍体基因组包含600 - 800个成员。9.0 kb的组蛋白基因簇在基因组中并不相邻，而是被多达50 kb或更多的簇间隔序列与相邻的簇隔开；这些间隔序列中的一些或全部是主要位于着丝粒的卫星DNA的成员，其重复单元为2235 bp。