Pendás A M, Morán P, Garciía-Vázquez E
Departmento de Biologia Funcional, Area de Genetica, Facultad de Medicina, Universidad de Oviedo, Spain.
Chromosome Res. 1993 May;1(1):63-7. doi: 10.1007/BF00710608.
The ribosomal rRNA genes have been mapped by fluorescent in situ hybridization (FISH) to brown trout chromosomes. One major NOR chromosome pair and 8 novel minor NOR chromosome pairs have been found. Both major and minor NORs were closely related to polymorphic heterochromatin, as revealed by FISH and C-banding. These results are discussed with respect to NOR expression, the relationship between rDNA and heterochromatin, and evolutionary aspects.
核糖体rRNA基因已通过荧光原位杂交(FISH)定位到褐鳟染色体上。已发现一对主要的核仁组织区(NOR)染色体和8对新的次要NOR染色体。荧光原位杂交和C带分析显示,主要和次要的NOR均与多态性异染色质密切相关。本文就NOR的表达、rDNA与异染色质的关系以及进化方面对这些结果进行了讨论。