Reilly S, Timmis P, Beeden A G, Willis A T
J Clin Pathol. 1981 May;34(5):542-7. doi: 10.1136/jcp.34.5.542.
Anaerobic bacteria were isolated from all tonsils removed from children at routine tonsillectomy; 75.6% of specimens yielded moderate to heavy growth and 80% of tonsils contained more than one anaerobic species. This recovery rate fell to 56% after a 10-day course of metronidazole before tonsillectomy--in only 14.6% of cases were anaerobes isolated in significant numbers. Surface swabbing of the tonsils permitted recovery of a similar spectrum of anaerobic bacteria but resulted in an overall loss of both aerobic and anaerobic pathogens. A comparison was made between the flora of acutely inflamed tonsils and "healthy' tonsils: over 90% of both groups yielded anaerobic bacteria, but they were present in significant numbers in 56.2% of swabs taken from acutely inflamed tonsils compared with 24% of swabs from "healthy' children. The isolation rate for anerobic pathogens was 37.5% and 16% respectively.
在常规扁桃体切除术中，从所有切除的儿童扁桃体中均分离出厌氧菌；75.6%的标本生长为中度至重度，80%的扁桃体含有一种以上的厌氧菌。在扁桃体切除术前使用甲硝唑进行为期10天的疗程后，这一恢复率降至56%——只有14.6%的病例中分离出大量厌氧菌。对扁桃体进行表面擦拭可回收类似种类的厌氧菌，但导致需氧菌和厌氧菌病原体总体损失。对急性发炎扁桃体和“健康”扁桃体的菌群进行了比较：两组中超过90%的样本产生了厌氧菌，但在从急性发炎扁桃体采集的拭子中，56.2%的样本中厌氧菌数量较多，而从“健康”儿童采集的拭子中这一比例为24%。厌氧菌病原体的分离率分别为37.5%和16%。
